Bison is a gourmet product that offers significant health benefits, including a high proportion of protein relative to calories because of its density. Bison is an extremely lean protein with 1/3 less fat than beef, and it is also lower in cholesterol. A single daily serving also provides most of the iron, zinc and antioxidant selenium that your body needs. This chart compares the nutrient composition of bison with other proteins. With 40% more protein than beef, you can eat 1/3 less bison and be satisfied.